Triluma cream is a prescription medication that combines three active ingredients: fluocinolone acetonide (0.01%), hydroquinone (4%), and tretinoin (0.05%). This topical dermatologic formulation is primarily used for the treatment of moderate to severe melasma, a skin condition characterized by dark patches or hyperpigmentation, often occurring on the face. Each component of Triluma cream serves a specific purpose in addressing different aspects of the condition.

Fluocinolone acetonide, a corticosteroid, helps reduce inflammation and skin redness. Hydroquinone is a skin-lightening agent that inhibits the production of melanin, the pigment responsible for skin color. Tretinoin, a retinoid, promotes skin cell turnover and enhances the ***** of other active ingredients. Together, these components work synergistically to mitigate the discoloration associated with melasma.