It is an opioid prescription drug tHydrocodone and acetaminophen are the two main active components in the brand-name drug Vicodin.hat is used to treat moderate to severe pain. Here are some crucial details about Vicodin. Vicodin combines acetaminophen (commonly referred to as paracetamol), a non-opioid painkiller and fever reducer, with hydrocodone, an opioid analgesic. The interaction improves hydrocodone's ability to relieve pain.
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