Manforce 50 mg is sildenafil 50 mg, and it is a standard starting dose for many adult men with erectile dysfunction. The usual recommendation is 50 mg about 1 hour before ***** activity, with a maximum of 100 mg once in 24 hours, depending on effectiveness and tolerability. D DailyMed +1 Who can generally use it? It may be appropriate for an adult man who: Has difficulty getting or maintaining an erection. Is medically fit enough for ***** activity. Isn't taking medicines that dangerously interact with sildenafil. Who should NOT take it without medical advice? Do not use sildenafil with nitrate medicines such as nitroglycerin or isosorbide, or with recreational “poppers,” because blood pressure can fall dangerously. It is also contraindicated with riociguat. D DailyMed +1 Extra caution is needed with certain heart conditions, very low blood pressure, alpha-blockers, significant liver/kidney disease, or a history of certain eye problems. In older adults and people with severe kidney or liver impairment, 25 mg may be a more appropriate starting dose. D DailyMed Important: Don't take Manforce 50 mg together with Manforce 100, Tazzle/tadalafil, or Super Kamagra unless a doctor specifically directs you to do so. If you tell me your age and whether you take any heart/BP/prostate medicines, I can tell you whether 50 mg is generally a reasonable dose and what precautions apply.